{"355201":{"#nid":"355201","#data":{"type":"event","title":"Byoung-il Bae, Harvard Medical School","body":[{"value":"\u003Cp\u003EBig and Convoluted Brain Science\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBig and Convoluted Brain Science\u003C\/p\u003E\u003Cp\u003EThe highly enlarged and convoluted human brain contains approximately 86 billion neurons and a similar number of glia, resulting in extraordinary mental abilities as well as sufferings. Using human genetics and mouse models, I have elucidated (1) how a non-coding element controls cortical development in the human language area and surrounding regions, and (2) how centrosomal proteins control brain size. I will endeavor to elucidate molecular mechanisms underlying human cerebral cortical expansion and convolution, using genetically modified ferrets and human stem cell-derived cerebral organoids (in addition to mouse models) combined with powerful comparative genomics. Ultimately, I hope to understand how structural changes in the human brain have enabled acquisition of novel neurocognitive functions throughout human evolution.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Byoung-il Bae, Harvard Medical School"}],"uid":"27964","created_gmt":"2014-12-12 10:38:08","changed_gmt":"2017-04-13 21:20:56","author":"Jasmine Martin","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2015-01-15T10:00:00-05:00","event_time_end":"2015-01-15T10:00:00-05:00","event_time_end_last":"2015-01-15T10:00:00-05:00","gmt_time_start":"2015-01-15 15:00:00","gmt_time_end":"2015-01-15 15:00:00","gmt_time_end_last":"2015-01-15 15:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1275","name":"School of Biological Sciences"}],"categories":[],"keywords":[{"id":"112141","name":"Byoung-il Bae"},{"id":"2863","name":"Todd Streelman"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78751","name":"Undergraduate students"},{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EIf you have questions about logistics or would like to set up an appointment with the speaker, please contact the School of Biology\u0027s administrative office at \u003Ca href=\u0022mailto:bio-admin@biology.gatech.edu\u0022\u003Ebio-admin@biology.gatech.edu\u003C\/a\u003E.\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}