{"390171":{"#nid":"390171","#data":{"type":"event","title":"Biomedical Engineering Seminar","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u201cShaping Nanomedicines for Hard-to-Treat Cancers\u201d\u0026nbsp;\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003E\u003Cstrong\u003EEfstathios (Stathis) Karathanasis, Ph.D.\u003C\/strong\u003E\u003Cstrong\u003E\u003Cbr \/\u003E\u003C\/strong\u003E\u003Cstrong\u003EAssistant Professor\u003C\/strong\u003E\u003Cstrong\u003E\u003Cbr \/\u003E\u003C\/strong\u003E\u003Cstrong\u003ECase Western Reserve University\u003Cbr \/\u003E\u003C\/strong\u003E\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ESeminar\u0026nbsp;will be made available via videoconference in the Health Sciences Research Building, room E 160 and Technology Enterprise Park, room 104.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe\u0026nbsp;Karathanasis Laboratory for Cancer Nanotechnology focuses on\u0026nbsp;nanomedicine and its translational applications on cancer imaging and therapy. Specifically, our research program\u0026nbsp;exploits the\u0026nbsp;engineerable nature of nanoparticle technology to develop clinically relevant\u0026nbsp;therapeutic and imaging\u0026nbsp;agents for hard-to-treat cancers based on the integration of nanotechnology, oncology, imaging science and cancer biology. Using \u003Cem\u003Emultimodal \u003C\/em\u003E\u003Cem\u003Ein vivo \u003C\/em\u003E\u003Cem\u003Eimaging and 3D histological\u0026nbsp;\u003C\/em\u003Eanalyses, we study the relation between the design of nanoparticles (\u003Cem\u003Ee.g.\u003C\/em\u003E, structure, size, shape) and their navigation through different biological processes to extract design parameters that improve the overall\u0026nbsp;\u003Cem\u003Ein vivo\u003C\/em\u003E\u0026nbsp;performance of nanomedicines. Taking under consideration that tumors consist of a dynamic microenvironment that undergoes spatiotemporal changes, this feedback resulted in the design of various types of chain-like nanoparticles for targeting the microenvironment of hard-to-reach cancers, such as metastatic disease and invasive brain tumors. In addition to the development of\u0026nbsp;contemporary therapeutic\u0026nbsp;paradigms, our lab\u0026nbsp;develops\u0026nbsp;nanoparticle imaging agents\u0026nbsp;for MRI, CT and nuclear imaging to enable non-invasive \u003Cem\u003Ein vivo\u003C\/em\u003E interrogation and highly accurate diagnosis of disease.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003E\u003Cbr \/\u003E\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EFaculty Host: \u003C\/strong\u003E\u003Ca href=\u0022https:\/\/www.bme.gatech.edu\/bme\/faculty\/Johnna-S.-Temenoff\u0022\u003EJohnna Temenoff\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBiomedical Engineering Seminar - \u0022Shaping Nanomedicines for Hard-to-Treat Cancers\u0022 - Efstathios (Stathis) Karathanasis, Ph.D., Case Western Reserve University.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"\u0022Shaping Nanomedicines for Hard-to-Treat Cancers\u0022 - Efstathios Karathanasis, Ph.D., Case Western Reserve University"}],"uid":"27159","created_gmt":"2015-03-24 15:00:43","changed_gmt":"2017-04-13 21:19:41","author":"Vickie Okrzesik","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2015-04-02T12:00:00-04:00","event_time_end":"2015-04-02T13:00:00-04:00","event_time_end_last":"2015-04-02T13:00:00-04:00","gmt_time_start":"2015-04-02 16:00:00","gmt_time_end":"2015-04-02 17:00:00","gmt_time_end_last":"2015-04-02 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"1613","name":"Biomedical Engieering"},{"id":"385","name":"cancer"},{"id":"122301","name":"Nanomedicines"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78751","name":"Undergraduate students"},{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EFaculty Host: \u003C\/strong\u003E\u003Ca href=\u0022mailto:%20johnna.temenoff@bme.gatech.edu\u0022\u003EJohnna Temenoff\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}