{"52430":{"#nid":"52430","#data":{"type":"event","title":"CSE Seminar: Alex Zelikovsky","body":[{"value":"\u003Cp class=\u0022MsoPlainText\u0022\u003E\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EAlex Zelikovsky\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EProfessor, Computer Science Department, Georgia State University\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EFor more information please contact Dr. Mark Borodovsky at \u003Ca href=\u0022mailto:fujimoto@cc.gatech.edu\u0022\u003Eborodovsky@ gatech.edu\u003C\/a\u003E\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E\u0022Virus Quasispecies Assembly using Network Flows\u0022\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EAbstract:\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EUnderstanding how the genomes of viruses mutate and evolve within infected individuals is critically important in epidemiology. In this talk I focus on optimization problems in sequence assembly for viruses based on 454 Lifesciences system. Several formulations of the quasispecies assembly problem and a measure of the assembly quality will be given. I will describe a scalable assembling method for quasispecies based on network flow and maximum likelihood formulations and then give details of existing and novel methods for reliably assembling quasipsecies that have very long common segments.\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EFinally, I report the results of assembling 44 quasispecies from the\u00a0 1700 bp long E1E2 region of Hepatitis C Virus.\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E(Joint work with K. Wesbrooks, I. Astrovskaya (GSU) D. C. Rendon, Y.\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EKhudyakov (CDC), P. Berman (Penn State)\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EBio:\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EAlex Zelikovsky is a Professor at Computer Science Department, Georgia State University. His research areas include discrete algorithms and applications in bioinformatics, VLSI CAD, and wireless networks. Out of his 160 refereed publications, 4 received best paper awards at the top international conferences and one journal paper won SIAM Outstanding Paper Prize. He is a chair and PC member of many international conferences, an editor of several special issues and on the editorial board of 5 international journals.\u003C\/p\u003E\n\u003Cp\u003E~~~~~~~~~~~~~~~~~~~~\u003C\/p\u003E\n\u003Cp\u003EYou are cordially invited to attend a reception between 1:30-2:00, before the seminar, to chat informally with faculty and students.\u003C\/p\u003E\n\u003Cp\u003E\u003C\/p\u003E\n\u003Cp\u003ERefreshments will be provided\u003C\/p\u003E\n\u003Cp\u003ETo receive future announcements, please sign up to the cse-seminar email list:\u003Ca href=\u0022https:\/\/mailman.cc.gatech.edu\/mailman\/listinfo\/cse-seminar\u0022\u003E\u003Cbr \/\u003E\u003C\/a\u003E\u003C\/p\u003E\n\u003Cp\u003E\u003Ca href=\u0022https:\/\/mailman.cc.gatech.edu\/mailman\/listinfo\/cse-seminar\u0022\u003Ehttps:\/\/mailman.cc.gatech.edu\/mailman\/listinfo\/cse-seminar\u003C\/a\u003E\u003C\/p\u003E\n\u003Cp\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27154","created_gmt":"2010-02-11 15:51:40","changed_gmt":"2016-10-08 01:49:43","author":"Louise Russo","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2009-09-25T15:00:00-04:00","event_time_end":"2009-09-25T16:00:00-04:00","event_time_end_last":"2009-09-25T16:00:00-04:00","gmt_time_start":"2009-09-25 19:00:00","gmt_time_end":"2009-09-25 20:00:00","gmt_time_end_last":"2009-09-25 20:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"47223","name":"College of Computing"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"Lometa Mitchell","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}