{"52567":{"#nid":"52567","#data":{"type":"event","title":"CSE Seminar","body":[{"value":"\u003Cp\u003ECSE\/Seminar Announcement\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E\u00a0\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EBy: Eberhard O. Voit\u003C\/p\u003E\n\u003Cp\u003EIntegrative BioSystems Institute\u003C\/p\u003E\n\u003Cp\u003EDepartment of Biomedical Engineering, Georgia Institute of Technology\u003C\/p\u003E\n\u003Cp\u003EDate: Friday, February 13, 2009\u003C\/p\u003E\n\u003Cp\u003ETime: 2:00pm-3:00pm\u003C\/p\u003E\n\u003Cp\u003ELocation: Klaus 2447 \u003C\/p\u003E\n\u003Cp\u003EFor more information please contact \u00a0Dr. Richard Fujimoto; \u003Ca href=\u0022mailto:fujimoto@cc.gatech.edu\u0022\u003Efujimoto@cc.gatech.edu\u003C\/a\u003E\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003E\u00a0\u003C\/strong\u003E\u003C\/p\u003E\n\u003Cp\u003E\u00a0\u003C\/p\u003E\n\u003Cp\u003ETitle:\u003C\/p\u003E\n\u003Cp\u003ETranslation of Biological Systems into Computable Models\u003C\/p\u003E\n\u003Cp\u003E\u00a0\u003C\/p\u003E\n\u003Cp\u003E\u00a0\u003C\/p\u003E\n\u003Cp\u003EAbstract:\u003C\/p\u003E\n\u003Cp\u003EThe grand challenge of computational systems biology is the translation of biological systems into mathematical structures that permit computational analysis, interrogation, and simulation. This translation process requires two major steps, which however are not independent of each other. One is the construction of a suitable mathematical model representation and the second is the determination of parameter values that match the model to experimental data, thereby making it realistic. This presentation will discuss challenges, as well as partial solutions, for both steps. At the core of the discussion will be a suitable default approach for initiating both steps, namely a \u201ccanonical\u201d modeling framework called Biochemical Systems Theory. The adjective \u201ccanonical\u201d refers to the pre-described mathematical structures of models within this framework, which offer valuable guidance for model construction and analysis. While focusing primarily on issues of model design and parameter estimation, I will also demonstrate the methods with actual applications to biological data.\u003C\/p\u003E\n\u003Cp\u003E\u00a0\u003C\/p\u003E\n\u003Cp\u003E~~~~~~~~~~~~~~~\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EYou are cordially invited to attend a reception that will follow the seminar to chat informally with faculty and students. Refreshments will be provided.\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E\u00a0\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003ETo receive future announcements, please sign up to the cse-seminar email list:\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E\u00a0\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E\u003Ca title=\u0022https:\/\/mailman.cc.gatech.edu\/mailman\/listinfo\/cse-seminar\u0022 href=\u0022https:\/\/mailman.cc.gatech.edu\/mailman\/listinfo\/cse-seminar\u0022\u003Ehttps:\/\/mailman.cc.gatech.edu\/mailman\/listinfo\/cse-seminar\u003C\/a\u003E\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003E\u00a0\u003C\/p\u003E\n\u003Cp class=\u0022MsoPlainText\u0022\u003EHope to see you there!\u003C\/p\u003E\n\u003Cp\u003E\u00a0\u003C\/p\u003E\n\u003Cp\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27154","created_gmt":"2010-02-11 15:56:32","changed_gmt":"2016-10-08 01:49:53","author":"Louise Russo","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2009-02-13T13:00:00-05:00","event_time_end":"2009-02-13T14:00:00-05:00","event_time_end_last":"2009-02-13T14:00:00-05:00","gmt_time_start":"2009-02-13 18:00:00","gmt_time_end":"2009-02-13 19:00:00","gmt_time_end_last":"2009-02-13 19:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"47223","name":"College of Computing"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"Lometa Mitchell","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}