The presentation gives an overview of the Microscale Thermophoresis (MST) technology. MST is a powerful method to quantify biomolecular interactions. It measures the motion of molecules along microscopic temperature gradients, detecting changes in their hydration shell, charge, or size. In combination with high-precision fluorescence detection, MST provides a flexible, robust, and rapid method to measure molecular interactions using miniscule sample quantities. Applications range from small-molecule screening and drug discovery to analyzing interactions of multi-protein complexes. Technical details, technology benefits, and application examples will be described. Assay development, data analysis, and best practices will also be discussed.

Complimentary Lunch Provided with Registration.

Agenda:

11:50 AM – 12:00 PM
Registration and Lunch Pick Up

12:00 PM – 12:10 PM
 Welcome Address and Seminar Overview

12:10 PM – 1:00 PM
Session 1: Applications of Microscale Thermophoresis

1:00 PM – 1:30 PM
Session 2: MST Lab Demonstration

1:30 PM - 2:00 PM
IEN Cleanroom Tour

Complimentary Lunch Provided with Registration.