{"596175":{"#nid":"596175","#data":{"type":"event","title":"GT Neuro Seminar Series","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u0026quot;The Self-Repairing Brain: Mechanisms Underlying Plasticity in Sensory Pathways?\u0026quot;\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ESarah Pallas, Ph.D.\u003Cbr \/\u003E\r\nProfessor, Biology and Neuroscience\u003Cbr \/\u003E\r\nGeorgia State University\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EResearch in the Pallas lab is aimed at understanding the cellular and molecular mechanisms underlying development and plasticity of sensory pathways in the brain.\u0026nbsp;Our approach is to alter normal developmental programs, either through sensory deprivation or surgical alteration, and study how the neural circuits compensate for the alterations.\u0026nbsp;We have discovered that at both the cortical and subcortical levels, circuits in sensory pathways exhibit remarkable levels of compensatory plasticity.\u0026nbsp;By studying how circuits can be rewired and how excitatory and inhibitory synapses respond, we have demonstrated that inhibitory synaptic plasticity is much more significant than previously appreciated.\u0026nbsp;We are currently investigating how the axon guidance factor ephrin-A and the neurotrophic factor BDNF are involved in orchestrating these plastic responses.\u0026nbsp;Understanding the mechanisms underlying compensatory plasticity is necessary in order to harness them for therapeutic purposes.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"\u0022The Self-Repairing Brain: Mechanisms Underlying Plasticity in Sensory Pathways?\u0022 - Sarah Pallas, Ph.D., Georgia State University"}],"uid":"27561","created_gmt":"2017-09-19 18:45:37","changed_gmt":"2017-09-21 12:45:19","author":"Angela Ayers","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2017-10-30T12:15:00-04:00","event_time_end":"2017-10-30T13:15:00-04:00","event_time_end_last":"2017-10-30T13:15:00-04:00","gmt_time_start":"2017-10-30 16:15:00","gmt_time_end":"2017-10-30 17:15:00","gmt_time_end_last":"2017-10-30 17:15:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"},{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"248","name":"IBB"},{"id":"172970","name":"go-neuro"},{"id":"126591","name":"go-NeuralEngineering"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:crozell@gatech.edu\u0022\u003EChris Rozell \u003C\/a\u003E- faculty host\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}