{"599031":{"#nid":"599031","#data":{"type":"event","title":"Integrated Cancer Research Center Seminar Series","body":[{"value":"\u003Cp\u003E\u003Cbr \/\u003E\r\n\u003Cstrong\u003E\u0026ldquo;Roles of Neural Stem and Progenitor Cells in the Development of Benign and Malignant Brain Tumors\u0026rdquo;\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EYuan Zhu, Ph.D.\u003Cbr \/\u003E\r\nProfessor\u003Cbr \/\u003E\r\nScientific Director, Gilbert Family Neurofibromatosis Institute\u003Cbr \/\u003E\r\nChildren\u0026rsquo;s National Medical Center\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThis presentation will focus on using genetically engineered mouse (GEM) models to study the role of neural stem and progenitor cells in the development of benign Grade I glioma and Grade IV malignant glioma, also known as glioblastoma (GBM), the most common primary brain in children and adults, respectively. Our study identifies a critical therapeutic window for targeting glial precursor cells during development in the context of neurofibromatosis type 1 (NF1)-associated Grade I glioma. Furthermore, we also reveal a less proliferative precursor population for highly aggressive GBMs, but surprisingly, these two GBM populations are anatomically located in the different regions of the brain.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"\u201cRoles of Neural Stem and Progenitor Cells in the Development of Benign and Malignant Brain Tumors\u201d - Yuan Zhu, Ph.D. - Children\u0027s National Medical Center"}],"uid":"27349","created_gmt":"2017-11-21 18:00:57","changed_gmt":"2017-11-26 19:05:33","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2017-11-30T13:00:00-05:00","event_time_end":"2017-11-30T14:00:00-05:00","event_time_end_last":"2017-11-30T14:00:00-05:00","gmt_time_start":"2017-11-30 18:00:00","gmt_time_end":"2017-11-30 19:00:00","gmt_time_end_last":"2017-11-30 19:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"https:\/\/childrensnational.org\/research-and-education\/center-for-cancer-immunology-research\/research-laboratories\/yuan-zhu-laboratory","title":"Zhu profile"},{"url":"http:\/\/icrc.gatech.edu","title":"Integrated Cancer Research Institute"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"126571","name":"go-PetitInstitute"},{"id":"52061","name":"ICRC Seminar"},{"id":"168803","name":"go-icrc-events"},{"id":"172695","name":"go-icrc"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:yuhong.fan@biology.gatech.edu\u0022\u003EYuhong Fan\u003C\/a\u003E - faculty host\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}