{"600672":{"#nid":"600672","#data":{"type":"event","title":"Integrated Cancer Research Center Seminar Series","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u0026quot;Microfluidic Studies of Cancer\u0026quot;\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EShuichi Takayama, Ph.D.\u003Cbr \/\u003E\r\nProfessor\u003Cbr \/\u003E\r\nDepartment of Biomedical Engineering\u003Cbr \/\u003E\r\nGeorgia Tech\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThis presentation will give an overview of microfluidic technologies that aim to better analyze and bioengineer tumors. The presentation will describe microchannel- and droplet-based in vitro models of tumors. The microfluidic technologies are used to study cell signaling, migration and metastasis as well as to perform drug screening.\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003ESpecific applications that will be introduced include:\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E(1) Use of laminar flow to stimulate parts of single cell and reveal differences in subcellular EGF signaling in normal vs cancer cells.\u003Cbr \/\u003E\r\n(2) The role of the chemokine, CXCL12, and its receptors CXCR4 and CXCR7 in mediating intravascular tumor adhesion and chemotaxis.\u003Cbr \/\u003E\r\n(3) DNA vector microprinting using aqueous two phase systems to screen cancer invasion genes.\u003Cbr \/\u003E\r\n(4) Hanging drop-based high-throughput tumor spheroid drug testing.\u003Cbr \/\u003E\r\n(5) Efforts to incorporate stromal cells and immune cells into the in vitro systems.\u003Cbr \/\u003E\r\n\u0026nbsp;\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"\u0022Microfluidic Studies of Cancer\u0022 - Shuichi Takayama, Ph.D. - Georgia Tech"}],"uid":"27349","created_gmt":"2018-01-11 14:22:05","changed_gmt":"2018-01-11 14:26:20","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2018-01-16T16:00:00-05:00","event_time_end":"2018-01-16T17:00:00-05:00","event_time_end_last":"2018-01-16T17:00:00-05:00","gmt_time_start":"2018-01-16 21:00:00","gmt_time_end":"2018-01-16 22:00:00","gmt_time_end_last":"2018-01-16 22:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/icrc.gatech.edu","title":"Integrated Cancer Research Institute"},{"url":"http:\/\/microfluidics.gatech.edu\/","title":"Takayama Lab"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"126571","name":"go-PetitInstitute"},{"id":"168803","name":"go-icrc-events"},{"id":"172695","name":"go-icrc"},{"id":"52061","name":"ICRC Seminar"},{"id":"49721","name":"ICRC"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:john.mcdonald@biology.gatech.edu\u0022\u003EJohn McDonald\u003C\/a\u003E - faculty host\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}