{"644639":{"#nid":"644639","#data":{"type":"news","title":"Beam Therapeutics Acquires Dahlman\u2019s Gene Therapy Startup","body":[{"value":"\u003Cp\u003EA startup spun out of Georgia Tech in 2018 to guide gene therapies using lipid nanoparticle technology has been acquired by Beam Therapeutics in an \u003Ca href=\u0022https:\/\/investors.beamtx.com\/news-releases\/news-release-details\/beam-therapeutics-announces-acquisition-guide-therapeutics\u0022\u003Eall-stock deal announced Feb. 23\u003C\/a\u003E.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Ca href=\u0022https:\/\/guidetx.com\/\u0022\u003EGuide Therapeutics\u003C\/a\u003E was born out of \u003Ca href=\u0022https:\/\/www.bme.gatech.edu\/bme\/dna-faster-data-more-storage-better-drugs\u0022\u003EDNA barcoding and data storage work in the lab of James Dahlman\u003C\/a\u003E, \u003Ca href=\u0022https:\/\/www.bme.gatech.edu\/bme\/faculty\/James-Dahlman\u0022\u003Eassistant professor in the Wallace H. Coulter Department of Biomedical Engineering\u003C\/a\u003E at Georgia Tech and Emory University. Dahlman co-founded Guide to efficiently develop safe gene therapies with a former graduate researcher in his lab, Cory Sago.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe company uses patented DNA barcoding technology to tag lipid nanoparticles and then simultaneously test thousands of the molecules in search of those that can deliver drugs to different kinds of cells in the body.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EOne FDA-approved a drug uses the lipid nanoparticle delivery approach to target cells in the liver. \u003Ca href=\u0022https:\/\/guidetx.com\/\u0022\u003EGuide is searching for nanoparticles\u003C\/a\u003E that will work to deliver therapies to other cells and says it can generate drug delivery data at a rate 15,000-fold higher than traditional experiments.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EGuide received project management and business mentorship from the Coulter Department\u0026rsquo;s \u003Ca href=\u0022https:\/\/biolocity.gatech.edu\/\u0022\u003EBiolocity technology commercialization program\u003C\/a\u003E in 2019. The company also won a \u003Ca href=\u0022https:\/\/www.businesswire.com\/news\/home\/20200130005487\/en\/Georgia-Bio-Names-2020-Golden-Helix-Award\u0022\u003EDeal of the Year award from Georgia Bio\u003C\/a\u003E in 2020 after an initial equity investment from GreatPoint Ventures.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Ca href=\u0022https:\/\/medcitynews.com\/2021\/02\/beam-makes-120m-bet-that-guidetxs-tech-brings-gene-editing-beyond-the-liver\/\u0022\u003E\u003Cstrong\u003ERead more about the acquisition.\u003C\/strong\u003E\u003C\/a\u003E\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EGuide Therapeutics was born from James Dahlman\u0026#39;s work on DNA barcodes.\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":[{"value":"Guide Therapeutics was born from James Dahlman\u0027s work on DNA barcodes."}],"uid":"27446","created_gmt":"2021-02-24 13:37:37","changed_gmt":"2021-02-26 18:28:31","author":"Joshua Stewart","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2021-02-24T00:00:00-05:00","iso_date":"2021-02-24T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"644640":{"id":"644640","type":"image","title":"James Dahlman (16x9)","body":null,"created":"1614195529","gmt_created":"2021-02-24 19:38:49","changed":"1614195739","gmt_changed":"2021-02-24 19:42:19","alt":"James Dahlman headshot","file":{"fid":"244758","name":"Dahlman-James-By-Roger-Slavens-h.jpg","image_path":"\/sites\/default\/files\/images\/Dahlman-James-By-Roger-Slavens-h.jpg","image_full_path":"http:\/\/tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Dahlman-James-By-Roger-Slavens-h.jpg","mime":"image\/jpeg","size":189694,"path_740":"http:\/\/tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Dahlman-James-By-Roger-Slavens-h.jpg?itok=K3OCHT7z"}}},"media_ids":["644640"],"related_links":[{"url":"https:\/\/medcitynews.com\/2021\/02\/beam-makes-120m-bet-that-guidetxs-tech-brings-gene-editing-beyond-the-liver\/","title":"Read More: \u0022Beam makes $120M bet that GuideTx\u2019s tech brings gene editing beyond the liver\u0022"},{"url":"https:\/\/investors.beamtx.com\/news-releases\/news-release-details\/beam-therapeutics-announces-acquisition-guide-therapeutics","title":"Beam Therapeutics News Release"},{"url":"https:\/\/www.bme.gatech.edu\/bme\/dna-faster-data-more-storage-better-drugs","title":"Read More: \u0022DNA: Faster Data, More Storage, Better Drugs\u0022"},{"url":"https:\/\/www.bme.gatech.edu\/bme\/faculty\/James-Dahlman","title":"James Dahlman"},{"url":"https:\/\/guidetx.com\/","title":"Guide Therapeutics"},{"url":"https:\/\/biolocity.gatech.edu\/","title":"Biolocity"}],"groups":[{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"145161","name":"James Dahlman"},{"id":"249","name":"Biomedical Engineering"},{"id":"182840","name":"Biolocity"},{"id":"179935","name":"DNA barcode"},{"id":"173419","name":"DNA barcoding"},{"id":"186748","name":"lipid nanoparticle"},{"id":"187109","name":"Guide Therapeutics"},{"id":"166994","name":"startups"},{"id":"11753","name":"acquisition"},{"id":"126571","name":"go-PetitInstitute"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:jstewart@gatech.edu\u0022\u003EJoshua Stewart\u003C\/a\u003E\u003C\/p\u003E\r\n","format":"limited_html"}],"email":["jstewart@gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}