{"660159":{"#nid":"660159","#data":{"type":"event","title":"Georgia Tech Neuro Seminar Series","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u003Ca href=\u0022https:\/\/vet.uga.edu\/person\/anumantha-kanthasamy\/\u0022\u003EAnumantha Kanthasamy, Ph.D.\u003C\/a\u003E\u003Cbr \/\u003E\r\nProfessor\u003Cbr \/\u003E\r\nDepartment of Physiology and Pharmacology\u003Cbr \/\u003E\r\nDirector,\u0026nbsp;Center for Brain Science and Neurodegenerative Diseases\u003Cbr \/\u003E\r\nJohn H. \u0026ldquo;Johnny\u0026rdquo; Isakson Chair for Parkinson\u0026rsquo;s Research and Georgia Research Alliance Eminent Scholar\u003Cbr \/\u003E\r\nUniversity of Georgia\u003C\/strong\u003E\u003Cbr \/\u003E\r\n\u003Cbr \/\u003E\r\n\u003Cem\u003E*Lunch provided for in-person attendees\u003C\/em\u003E\u003Cbr \/\u003E\r\n\u003Cbr \/\u003E\r\n\u003Cstrong\u003E\u003Cem\u003E*To participate virtually, \u003C\/em\u003E\u003Ca href=\u0022https:\/\/gatech.zoom.us\/j\/96163544579?pwd=VXhJWVd1amhHdmNMNk1WbUNDVGkxUT09\u0022\u003E\u003Cem\u003ECLICK HERE\u003C\/em\u003E\u003C\/a\u003E\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EAnumantha Kanthasamy\u0026rsquo;s research program has been at the forefront in unraveling the cell signaling mechanisms underlying key pathophysiological processes of PD, including mitochondrial dysfunction, oxidative stress, dopaminergic therapy, aSyn protein aggregation, gut microbiota dysbiosis, exosome trafficking, neuroinflammation, and apoptosis. Furthermore he and his team recently adopted a highly sensitive RT-QuIC assay to successfully detect ultralow levels of pathologic \u0026alpha;Syn aggregates from serum, plasma, CSF and submandibular and skin samples from PD and related Parkinsonian disorders. Kanthasamy\u0026rsquo;s lab translational research efforts also involve testing the efficacy of several small-molecule, peptide, and probiotic therapeutics against select targets in various experimental models of PD such as MPTP, 6-OHDA, MitoPark, and \u0026alpha;Syn rodent models to advance them for further preclinical and clinical evaluations. The lab\u0026rsquo;s translational research efforts have resulted in several patent applications, including utility patent application 16\/287,437, \u0026ldquo;L-Dopa Microbiome Therapy.\u0026rdquo;\u0026nbsp;This knowledge is key to discovering new biomarkers and will advance the development of novel translational approaches for the treatment of neurodegenerative diseases like PD. Kanthasamy\u0026rsquo;s program has been continuously supported by multiple NIH grants from NIEHS and NINDS for over 20 years, and he is currently funded by NIEHS, NINDS, NIBIB, MJFF, and DoD grants. He has trained over 30 Ph.D. students and his current research program employs over 25 researchers, largely comprising graduate students.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EOverall his drive research projects in four major areas:\u003C\/p\u003E\r\n\r\n\u003Cul\u003E\r\n\t\u003Cli\u003ENovel apoptotic and compensatory signaling activated during neurotoxic insult in the dopaminergic neurodegenerative process;\u003C\/li\u003E\r\n\t\u003Cli\u003EProtein misfolding and neuroinflammatory mechanisms in neurotoxicity;\u003C\/li\u003E\r\n\t\u003Cli\u003EEpigenetic reprogramming in neurotoxic stress; and\u003C\/li\u003E\r\n\t\u003Cli\u003ETranslational biomarker and drug discovery in neurotoxicity and neurodegeneration.\u003C\/li\u003E\r\n\u003C\/ul\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Anumantha Kanthasamy, Ph.D. - University of Georgia"}],"uid":"27195","created_gmt":"2022-08-15 17:28:49","changed_gmt":"2022-08-15 17:50:54","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2022-09-26T12:15:00-04:00","event_time_end":"2022-09-26T13:15:00-04:00","event_time_end_last":"2022-09-26T13:15:00-04:00","gmt_time_start":"2022-09-26 16:15:00","gmt_time_end":"2022-09-26 17:15:00","gmt_time_end_last":"2022-09-26 17:15:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"},{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"187423","name":"go-bio"},{"id":"172970","name":"go-neuro"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"177814","name":"Postdoc"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:garrett.stanley@bme.gatech.edu\u0022\u003EGarrett Stanley, Ph.D.\u003C\/a\u003E - faculty host\u003Cbr \/\u003E\r\n\u003Ca href=\u0022mailto:connect@ibb.gatech.edu\u0022\u003Econnect@ibb.gatech.edu\u003C\/a\u003E - event inquiries\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}