{"669914":{"#nid":"669914","#data":{"type":"news","title":"Exploring the Genome\u2019s Dark Regions","body":[{"value":"\u003Cp\u003E\u003Ca href=\u0022https:\/\/bme.gatech.edu\/bme\/faculty\/Karmella-Haynes\u0022\u003EKarmella Haynes\u003C\/a\u003E wants to shine some light on the \u201cdark matter\u201d of the genome, and the National Science Foundation (NSF) is helping her flip the switch.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EHaynes, assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University, is leading a team of multi-disciplinary investigators who were awarded a four-year, \u003Ca href=\u0022https:\/\/www.nsf.gov\/awardsearch\/showAward?AWD_ID=2243665\u0026amp;HistoricalAwards=false\u0022\u003E$2.1 million grant from NSF\u003C\/a\u003E to explore this dark matter and illuminate how the genome controls living systems in all their diversity and complexity.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EIt\u2019s large space to explore. Only two percent of the human genome is known to provide instructions to build proteins, a process essential to higher functioning life. This leaves 98 percent of the genome as a biological frontier known as dark matter \u2013 these segments do not encode for protein, like the other two percent.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u201cA lot of progress has been made in studying this part of the genome, but what we don\u2019t know yet can be very useful,\u201d said Haynes, \u003Ca href=\u0022https:\/\/khayneslab.wordpress.com\/\u0022\u003Ewhose lab\u003C\/a\u003E works on the front line of synthetic biology, and is typically dedicated to protein engineering, including the investigation and design of chromatin-based systems for controlling gene expression in cancer and other cells.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Ca href=\u0022https:\/\/bme.gatech.edu\/bme\/news\/karmella-haynes-leads-exploration-genomes-dark-regions\u0022\u003E\u003Cstrong\u003ERead the full story on the Wallace H. Coulter Department of Biomedical Engineering website.\u003C\/strong\u003E\u003C\/a\u003E\u003C\/p\u003E\r\n","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBME\u0027s Karmella Haynes is leading a National Science Foundation project studying the mysteries and mechanisms of non-coding RNA.\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":[{"value":"BME\u0027s Karmella Haynes is leading a National Science Foundation project studying the mysteries and mechanisms of non-coding RNA."}],"uid":"27446","created_gmt":"2023-09-25 16:35:40","changed_gmt":"2023-09-25 16:39:43","author":"Joshua Stewart","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2023-08-22T00:00:00-04:00","iso_date":"2023-08-22T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"671814":{"id":"671814","type":"image","title":"Karmella Haynes","body":null,"created":"1693240553","gmt_created":"2023-08-28 16:35:53","changed":"1695659753","gmt_changed":"2023-09-25 16:35:53","alt":"Karmella Haynes","file":{"fid":"254947","name":"Karmella-Haynes-t.jpg","image_path":"\/sites\/default\/files\/2023\/09\/25\/Karmella-Haynes-t.jpg","image_full_path":"http:\/\/tlwarc.hg.gatech.edu\/\/sites\/default\/files\/2023\/09\/25\/Karmella-Haynes-t.jpg","mime":"image\/jpeg","size":1076399,"path_740":"http:\/\/tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2023\/09\/25\/Karmella-Haynes-t.jpg?itok=k9qiYkZ8"}}},"media_ids":["671814"],"groups":[{"id":"651783","name":"College of Engineering ADVANCE"},{"id":"289141","name":"Women in Engineering (WIE)"},{"id":"1237","name":"College of Engineering"}],"categories":[{"id":"145","name":"Engineering"}],"keywords":[{"id":"187959","name":"Karmella Haynes"},{"id":"249","name":"Biomedical Engineering"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:jerry.grillo@ibb.gatech.edu\u0022\u003EJerry Grillo\u003C\/a\u003E\u003Cbr \/\u003E\r\nWallace H. Coulter Department of Biomedical Engineering\u003C\/p\u003E\r\n","format":"limited_html"}],"email":["jerry.grillo@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}