Peter Kottke - Advisor, Andrei Fedorov, PhD 



Ambient Electrospray Ionization Mass Spectrometry Probe 



Ambient electrospray ionization mass spectrometry probes are an instrument for untargeted transient biochemical imaging. We have demonstrated dynamic, continuous single voxel imaging from sub-nL volumes, including high speed (1 s resolution) imaging of idealized samples. Lower speed (1 min resolution) continuous analysis of 3-D cell culture systems is made possible through incorporation of in-line microdialysis to enable salt removal. 



William Guerrant - Advisor, Adegboyega (Yomi) Oyelere, PhD 


Dual-Targeted Inhibitors of Histone Deacetylase and Topoisomerase II

The cancer chemotherapeutic of the future will modulate multiple targets while reducing debilitating side effects common to the therapy regimens of today. To this end we have created dual-targeted inhibitors of both histone deacetylase and topoisomerase II that display potent cytotoxicity against cancer cells and preserve activity against both enzymes.


The Graduate and Post-Doc (GaP) Seminar Series is a weekly event of biotechnology related research presentations by two graduate students or post-docs of IBB and is co-sponsored by BME. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD at manu.platt@bme.gatech.edu.