Pushing the Boundaries of Structural Biology: UGA Structural Genomics and Beyond

Biochemistry Division Seminar Series

Structural biology, using X-ray crystallography as a component, has advanced greatly during the last 30 plus years, as evidenced by the exponential growth in protein structures deposited into the Protein Data Bank. Key to the growth in the field is the development of synchrotron X-ray sources and molecular biology technologies. In addition, the development of structural genomics projects worldwide has not only put these advances into practice on a large scale, but also made significant, technological breakthroughs in all areas of X-ray structural biology. We are now at the stage where the determination of experimental 3D structures for many difficult targets may be possible, with some additional effort and attention. In this presentation, recent technological advances in the field will be summarized and future directions will be discussed.

For more information contact Prof. Raquel Lieberman (404-385-3663).